Abstract Background Randomized trials are considered the gold standard for making inferences about the causal effects of treatments.However, when protocol deviations occur, the baseline randomization of the trial is no longer sufficient to ensure unbiased estimation of the per-protocol effect: post-randomization, time-varying confounders must be su
DENV belongs to the Flaviviridae family and possesses a single-stranded RNA genome of positive polarity.DENV infection manifests in mild subclinical forms or severe forms that may be dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS).Despite a lot of effort worldwide, the exact mechanism underlying the pathogenesis of severe DENV infecti
BackgroundDiffuse lower-grade glioma (DLGG) in the central lobe is a challenge for safe resection procedures.To improve the extent of resection and reduce the risk of postoperative neurological deficits, we performed an awake craniotomy with cortical-subcortical direct electrical stimulation (DES) mapping for patients with DLGG located primarily wi
This study aims at establishing the Door Hinge Bush solvability of a fractional-order p-Laplacian boundary value problem involving both the left Caputo and right Riemann-Liouville fractional derivatives on the half-line.In order to overcome the nonlinearity of the fractional differential operator, we apply the Ge and Ren coincidence Anti-Spatter Sp
There is a growing threat of urban flooding, particularly in Pakistan that needs attention and requires effective management strategies.The chief trigger for urban flooding is the rapid and unplanned urbanization in areas where impermeable surface inhibits rainwater diffusion and changes the natural water flow.In many developed countries, a techniq